产品货号:
Z28803
中文名称:
TRIB3抗体
英文名称:
Anti-TRIB3 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-TRIB3 Antibody |
指标别名 | C20orf97;NIPK;SINK;SKIP3;TRB 3;TRB3;TRIB3;Tribbles homolog 3 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,IHC,IF |
基因名称 | TRIB3 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | TRB3 antibody was raised against a 17 amino acid peptide near the center of human TRB3.The immunogen is located within amino acids 100 - 150 of TRB3. |
计算分子量 | 40kDa |
成分 | TRB3 antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | TRB3 antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | TRB3 was initially identified as a novel kinase-like gene that was overexpressed in multiple human tumors and regulated by hypoxia (1).In the liver,TRB3 binds and inhibits AKT activity,leading to impaired insulin signaling (2),whereas in adipose tissue TRB3 is involved in the regulation of fatty acid oxidation through ubiquitination of Acetyl-CoA carboxylase (3).Endoplasmic reticulum (ER) stress induces TRB3 expression in skeletal muscle,leading to a decrease in insulin signaling and glucose uptake,suggesting that inhibition of TRB3 expression may be a potential therapeutic treatment for managing insulin resistance (4). |
Uniprot ID | Q96RU7 |
基因名全称 | Tribbles pseudokinase 3 |
蛋白名全称 | Tribbles pseudokinase 3 |
推荐稀释比 | TRB3 antibody can be used for detection of TRB3 by Western blot at 1 ~ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in mouse samples;Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples.All other applications and species not yet tested. |
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